-
Transaldolase (TAL)
Mabapi le Transaldolase
ES-TAL (Transaldolase): haholo-holo e bua ka threonine transaldolases, e ka susumetsang karabelo ea ho kopanya li-derivatives tsa β-hydroxyphenylalanine ka li-derivatives tsa threonine le benzaldehyde. TAL ke enzyme e itšetlehileng ka PLP. Ho na le mofuta o le mong feela oa sehlahisoa sa enzyme ea TAL (Nomoro e le ES-TAL101) e ntlafalitsoeng ke SyncoZymes, e ka sebelisoang ho kopanya β-hydroxyphenylalanine le li-derivatives tsa eona.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Ketoreductase (KRED)
Mabapi le Ketoreductase
Li-enzyme: Ke li-catalyst tsa baeloji tsa macromolecular, li-enzyme tse ngata ke liprotheine.
Ketoreductase: E boetse e bitsoa "Carbonyl reductase", ke lienzyme tse susumetsang karabelo ea redox e ka fetoloang pakeng tsa aldehydes / ketones le alcohols, 'me li hloka li-coenzymes e le phetisetso ea H joalo ka NADH kapa NADPH. Ho na le mekhahlelo e meraro e meholo ea KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), le Aldo-KetoReductases (AKRs). Mesebetsi ea catalytic ea tse tharo e tšoana, empa sebopeho le thepa li fapane haholo.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Transaminase (ATA)
Mabapi le transaminase
ATA e tsoang ho SyncoZymes: Ho na le mefuta e 66 ea lihlahisoa tsa enzyme ea ATA (Nomoro e le ES-ATA-101~ES-ATA-166) e ntlafalitsoeng ke SyncoZymes. SZ-ATA ke sesebelisoa se thusang ho susumetsa tlhahiso ea li-chiral amine tsa regio le stereoselective, li-amino acid le li-derivatives tsa tsona ho tsoa ho mefuta e fapaneng ea li-ketoacid tsa aliphatic le aromatic, aldehydes, ketones le ketoses.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Nitrilase (NIT)
Mabapi le Nitrilase
ES-NITs: Fetola sehlopha sa cyanide ka ho toba ho sehlopha sa carboxyl, ho lokisa asiti ea carboxylic, e sebelisoang haholo meriana, tšireletso ea tikoloho, indasteri ea lik'hemik'hale, lijo tse eketsang, masela, tlhahiso ea temo le masimo a mang.
Ho na le mefuta e 40 ea lihlahisoa tsa Nitrilase (NIT) (Nomoro e le ES-NIT-101~ES-NIT-140) e ntlafalitsoeng ke SyncoZymes. ES-NIT ke sesebelisoa se thusang ho susumetsa tlhahiso ea li-chiral carboxylic acid ka hydrolysis ea regio- le stereoselective ea mefuta e mengata ea li-nitrile tsa aliphatic le aromatic.Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Nitrile hydratase (NHT)
Mabapi le ES-NHTs
ES-NHTs: sehlopha sa metalloenzyme, e khemisang nitriles ka mokhoa o ikhethileng ho amide ea mantlha e tsamaellanang. Li sebelisoa haholo eseng feela bakeng sa ho kopanya li-amino acid, li-amide, li-carboxylic acid le li-derivatives tsa tsona, empa hape le bakeng sa ho lokisa meriana ea chiral. Ho na le mefuta e 24 ea li-hydratase tsa nitrile tse ntlafalitsoeng ke SyncoZymes (Palo e le ES-NHT-101 ~ ES-NHT-124).
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Amidase (AMD)
AMD ho tsoa ho SyncoZymes: Ho na le mefuta e 19 ea lihlahisoa tsa enzyme tsa AMD (Nomoro e le ES-AMD-101~ES-AMD-119) e ntlafalitsoeng ke SyncoZymes. SZ-AMD ke sesebelisoa se thusang ho susumetsa tlhahiso ea regio- le stereoselective ea chiral carboxylic acid le li-derivatives tsa tsona ho tsoa ho mefuta e fapaneng ea aliphatic le aromatic amides.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Ene reductase (ERED)
Mabapi le ene reductase
ES-EREDs: Ke karolo ea lelapa la li-enzyme tsa khale tse tšehla tse fokotsang C=C ka mokhoa o ikhethileng ka metsoako ea α, β-unsaturated e nang le lihlopha tse monyang lielektrone. Li sebelisoa haholo thutong ea li-derivatives tsa amino acid, lintho tse sebetsang, metsoako ea meriana, linoko le li-block tsa chiral.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Li-Oxynitrilase (HNL)
Mabapi le li-oxynitrilase
ES-HNLs: Enzyme ea sehlopha e susumetsang ka mokhoa o khethollang ho eketsoa ha HCN ho aldehydes (ketones) ho fumana alcohols ea cyanide ea mofuta oa R kapa S, e ka fetoloang habonolo hore e be mefuta e mengata ea lithethefatsi kapa li-intermediate tsa lithethefatsi ka mokhoa oa lik'hemik'hale.
Ho na le mefuta e 29 ea lihlahisoa tsa oxynitrilase (Nomoro e le ES-HNL-101～ES-HNL-129) e ntlafalitsoeng ke SyncoZymes. SZ-HNL ke sesebelisoa se thusang ho kopanya libaka le libaka tsa (R)-cyanohydrins kapa (S)-cyanohydrins ho tsoa mefuta e fapaneng ea aldehydes kapa esita le li-ketone tse nkhang hamonate, tse nang le monko o monate le tse sa fetoheng.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Nitro reductase (NTR)
Mabapi le nitro reductase
ES-NTRs: Ke li-flavoenzymes tse susumetsang phokotso e itšetlehileng ka NAD(P)H ea lihlopha tsa nitro tse itšetlehileng ka metsoako ea nitroaromatic le nitroheterocyclic ho ea ho hydroxylamino le/kapa li-amino derivatives. Li sebelisoa haholo ho etseng organic ea aromatic hydroxylamine le aromatic amine, kalafo ea hlahala, ho lemoha baeloji le ho senyeha ha litšila tsa tikoloho. Ho na le mefuta e 12 ea lihlahisoa tsa Nitro reductase (NTR) (Nomoro e le ES-NTR-101~ES-NTR-112) e ntlafalitsoeng ke SyncoZymes.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Aldolase (DERA)
ES-DERA: E ka susumetsa ka katleho ho eketsoa ha di-ketone tsa bafani ho di-receptor aldehydes ka stereoselective. Ho feta moo, karabelo e ka etswa ka tharollo ya metsi ya pH e sa nke lehlakore ntle le mehato e ikgethang ya tshireletso. Ke ya sehlopha sa I aldolase, e bopang motheo wa Shiff tshebetsong ya catalytic. Substrate e hokahantswe ka kopanelo le sehlopha sa amino sa sebaka se sebetsang ho qala ho robeha le ho thehwa ha tlamo. Phapang pakeng tsa DERA le di-aldolase tse ding ke hore di-substrate tseo di di susumetsang ke di-aldehydes mme di ka feta ho kolobisong ho sa feleng ha di-aldehydes.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Cytochrome P450 monooxygenase (CYP)
Mabapi le CYP
ES-CYPs: Sehlopha sa li-enzyme tsa redox tse nang le mercaptan-heme e le setsi se sebetsang sa ho susumetsa phetiso ea oksijene. Ke li-oxygenase tsa ho qetela 'me li hloka heme ho kenya tšebetsong oksijene.
Cytochrome P450 monooxygenase e susumetsa ho kenngwa ha oksijene, ho kenngwa ha oksijene le ho kenngwa ha hydroxylation ya alkyl, ho kenngwa ha hydroxylation le ho kenngwa ha ammonia, ho kenngwa ha sebabole, dealkylation (oksijene, sebabole, ammonia), ho kenngwa ha oksijene ka oxidative, ho ntshwa ha oksijene le ho ntshwa ha halogenation.
Ho na le mefuta e 8 ea lihlahisoa tsa cytochrome P450 monooxygenase (Nomoro e le ES-CYP-101～ES-CYP-108) e ntlafalitsoeng ke SyncoZymes.Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
-
Oxidase ea joala (AOX)
Mabapi le oxidase ea joala
ES-AOXs: Li-enzyme tsena li khona ho susumetsa oxidation ea mafura a alcohols kapa aryl-alcohols ho etsa aldehydes. Li sebelisa oksijene ea limolek'hule empa ha li hloke cofactor e ekelitsoeng ka ntle, le hydrogen peroxide e hlahisoang.
Ho na le mefuta e 6 ea lihlahisoa tsa oxidase ea joala (Nomoro e le ES-AOX-101~ES-AOX-106) e ntlafalitsoeng ke SyncoZymes. ES-AOX101 le ES-AOX102 li khetha li-substrate tsa alcohol tsa aliphatic, ES-AOX103~ ES-AOX105 li khetha li-substrate tsa alcohol tse nkhang hamonate, 'me ES-AOX106 ke cholesterol oxidase. SZ-AOX ke sesebelisoa se thusang ho potlakisa oxidation ea alcohols tse mafura kapa aryl-alcohols ho hlahisa aldehydes.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
