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Esterase&Lipase (PLE&CALB)
Mabapi le Esterase&Lipase
ES-PLEs: Sehlopha sa li-hydrolases tse susumetsang ho thehoa le ho senyeha ha li-ester bond.Ba ka nka karolo mefuteng e mengata ea karabelo ea biochemical, joalo ka esterification, transesterification le hydrolysis.Li sebelisoa haholo likarolong tse ngata tse kang ho lokisa lijo, indasteri ea lik'hemik'hale, biomedicine, meriana ea chiral le phekolo ea tikoloho.
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Mabapi le epoxide hydrolase
EH ke ether hydrolase e susumetsang stereoelective hydrolysis ea racemic epoxides ho hlahisa 1, 2-diol le epoxides optically active, e ka sebelisetsoang qeto ea chiral ea epoxides kapa ho lokisetsa li-chiral diols.Li sebelisoa haholo meriana le mafapheng a mang.Ho na le mefuta e 3 ea lihlahisoa tsa epoxide hydrolases (Palo e le ES-EH-101～ES-EH-103) e ntlafalitsoeng ke SyncoZymes.ES-EH ke sesebelisoa se sebetsang sa ho etsa tlhahiso ea li-alcohols tsa chiral ka stereoelective hydrolysis ea aliphatic le aromatics epoxides.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Mabapi le Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH e susumetsa dehydrogenation ea ammonium formate ho hlahisa carbon dioxide le ammonia, le ho fokotsa NAD ho NADH ka NAD e le electron receptor.FDH hangata e sebelisetsoa ho nchafatsa coenzyme NADH.Ho na le mefuta e 4 ea lihlahisoa tsa enzyme tsa FDH (ES-FDH-101~ES-FDH-104) tse entsoeng ke SyncoZymes, tseo har'a tsona ES-FDH102 e nang le ts'ebetso e phahameng ka ho fetisisa 'me ke FDH e khothalletsoang haholo.
Mofuta oa karabelo ea Catalytic:
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E-mail:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Mabapi le Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH e susumetsa dehydrogenation ea tsoekere ho hlahisa gluconic acid (lactone), le ho fokotsa NAD (P) + ho NAD (P) H, le NAD (P) + e le electron receptor.GDH e atisa ho sebelisoa bakeng sa tsosoloso ea coenzyme NAD(P)H masimong a biocatalysis ka enzyme e meng e ka sehloohong.Ho na le mefuta ea 10 ea lihlahisoa tsa enzyme ea GDH (ES-GDH-101~ES-GDH-110) e entsoeng ke SyncoZymes, eo har'a eona ES-GDH110 e nang le ts'ebetso e phahameng ka ho fetisisa 'me ke eona e khothalletsoang haholo-holo GDH.
Mofuta oa karabelo ea Catalytic:
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E-mail:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Mabapi le Monoamine oxidase
ES-MAO(Monoamine oxidase): MAO e etsa hore ho be le oxidative deamination ea monoamine ho hlahisa hydrogen peroxide, ammonia le aldehyde e tsamaisanang.Ts'ebetsong ea ts'ebetso, oksijene ea hlokahala joalo ka oxidant.Ho na le mefuta e 6 ea lihlahisoa tsa enzyme tsa MAO (Palo e le ES-MAO-101～ES-MAO-106) e ntlafalitsoeng ke SyncoZymes, e ka sebelisoang ho oxidative deamination ea metsoako ea monoamine.
Mofuta oa karabelo ea Catalytic:
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E-mail:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Mabapi le Lactate dehydrogenase
Ho na le mofuta o le mong oa sehlahisoa sa enzyme ea LDH (Palo e le ES-LDH) e ntlafalitsoeng ke SyncoZymes.LDH e ka baka phokotso ea pyruvate ho L-lactic acid, kapa phokotso ea li-α-keto acid tse ling tse tšoanang.Ts'ebetsong ea catalysis, NADH ea hlokahala joalo ka sepalangoang sa hydrogen.
Mofuta oa karabelo ea lactate dehydrogenasecatalytic
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E-mail:lchen@syncozymes.com
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Imine reductase (IRED)
Mabapi le Imine reductase
ES-IRED: Sehlopha sa li-enzyme tse etsang hore ho be le phokotso ea C=N bond ho CN bond.Ke ea enzyme ea redox, e nang le coenzyme NADPH bakeng sa lipalangoang tsa haedrojene.Ho ea ka khetho ea chiral ea lihlahisoa, li ka aroloa ka R-IRED le S-IRED.Li-syncozymes li hlahisitse 15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), e ka sebelisoang haholo phokotsong ea regioselective le stereoselective ea imines ho lokisa chiral amines.
Mofuta oa karabelo ea Catalytic:
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E-mail:lchen@syncozymes.com
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Nitrile reductase (NRED)
Mabapi le Nitrile reductase
Ho na le mofuta oa 3 oa sehlahisoa sa enzyme ea NRED (Palo e le ES-NRED101~ ES-NRED103) e entsoeng ke SyncoZymes.NRED e ka baka phokotso ea sehlopha sa nitrile ho amine.Ts'ebetsong ea catalysis, NADPH ea hlokahala joalo ka sepalangoang sa haedrojene.
Mofuta oa karabelo ea Nitrile reductasecatalytic
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
Mabapi le Phenylalanine dehydrogenase
ES-PDH: Sehlopha sa oxidoreductase.Karabelo e ntle e ka tsosa deamination ea oxidative ea letsoai la L phenylalanine ka pel'a NAD ho hlahisa letsoai la phenylpyruvate, 'me karabelo e ka morao e ka baka motsoako oa letsoai la amino acid le tsoang letsoai la phenylpyruvate.Li-syncozyme li hlahisitse lintho tse 8 tsa phenylalanine dehydrogenase (e nang le linomoro tsa ES-PDH-101~ES-PDH-108).ES-PDH e ka sebelisoa ho lokisa letsoai la phenylalanine kapa letsoai le tsamaisanang la amino acid ho tsoa letsoai la phenylpyruvic acid kapa tse tsoang ho tse ling.
Mofuta oa karabelo ea Catalytic:
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E-mail:lchen@syncozymes.com
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Leucine Dehydrogenase (LeuDH)
Mabapi le Leucine dehydrogenase
Ho na le mofuta o le mong oa sehlahisoa sa enzyme ea LeuDH (Palo e le ES-LeuDH-101) e entsoeng ke SyncoZymes.LeuDH e ka etsa hore reductive ammoniation ea 4-methylbutanoic acid (letsoai) ho L-leucine kapa oxidation ea leucine ho 4-methylbutanoic acid.ES-LeuDH e ka boela ea etsa hore ho be le phokotso ea amination ea α-keto acid e nang le sebopeho se ts'oanang ho lokisa li-derivatives tsa amino acid.Ts'ebetsong ea catalysis, NADH ea hlokahala joalo ka sepalangoang sa hydrogen.
Leucine dehydrogenasecatalytic reaction mofuta
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E-mail:lchen@syncozymes.com
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Threonine deaminase (TDA)
Mabapi le Threonine deaminase
ES-TDA (Threonine deaminase): protheine ea pyridoxal phosphate e susumetsang deamination ea threonine ho hlahisa 2-ketobutyric acid le ammonia.Pyridoxal 5-phosphate ea hlokahala joalo ka coenzyme tsamaisong ea catalytic.Ho na le mofuta o le mong feela oa sehlahisoa sa enzyme ea TDA (Palo e le ES-TDA) e ntlafalitsoeng ke SyncoZymes, e ka sebelisoang ho lokisa 2-ketobutyric acid kapa tse nkiloeng ho eona ho tsoa ho threonine.
Mofuta oa karabelo ea Catalytic:
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E-mail:lchen@syncozymes.com
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Amine Dehydrogenase (AmDH)
Mabapi le Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): enzyme e ka susumetsang ammoniation ea sehlopha sa carbonyl le ho e fokotsa ho sehlopha sa amino.Ke enzyme e itšetlehileng ka NADH ea coenzyme, 'me NADH e sebetsa e le mochine oa hydrogen.Ho na le mefuta e 4 ea lihlahisoa tsa enzyme tsa AmDH (Palo e le ES-AmDH101～ES-AmDH104) e ntlafalitsoeng ke SyncoZymes, e ka sebelisoang ho regioselective kapa stereoelective reductive amination ea aldehydes le ketone.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
