Epoxide hydrolase (EH)

Tlhaloso e Khutšoanyane:

Mabapi le epoxide hydrolase

EH ke ether hydrolase e susumetsang stereoelective hydrolysis ea racemic epoxides ho hlahisa 1, 2-diol le epoxides optically active, e ka sebelisetsoang qeto ea chiral ea epoxides kapa ho lokisetsa li-chiral diols.Li sebelisoa haholo meriana le mafapheng a mang.Ho na le mefuta e 3 ea lihlahisoa tsa epoxide hydrolases (Palo e le ES-EH-101～ES-EH-103) e ntlafalitsoeng ke SyncoZymes.ES-EH ke sesebelisoa se sebetsang sa ho etsa tlhahiso ea li-alcohols tsa chiral ka stereoelective hydrolysis ea aliphatic le aromatics epoxides.

Mofuta oa karabelo ea Catalytic:

Epoxide hydrolase EH2

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E-mail:lchen@syncozymes.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lintlha tsa Sehlahisoa:

Li-enzyme	Khoutu ea Sehlahisoa	Tlhaloso
Phofo ea enzyme	ES-EH-101~ ES-EH-103	sehlopha sa 3 Epoxide Hydrolases, 50 mg e 'ngoe le e' ngoe lintho tse 3 * 50mg / ntho, kapa bongata bo bong
Skrine Kit (SynKit)	ES-EH-300	sehlopha sa 3 Epoxide Hydrolases, 1 mg ka 'ngoe lintho tse 3 * 1mg / ntho

Melemo:

★ Boemo bo phahameng ba substrate.
★ Khetho e matla ea chiral.
★ Phetoho e phahameng.
★ Lihlahisoa tse fokolang.
★ Maemo a bonolo a karabelo.
★ Ho baballa tikoloho.

Litaelo tsa tšebeliso:

➢ Ka tloaelo, sistimi ea karabelo e tlameha ho kenyelletsa substrate, buffer solution (optimum reaction pH) le ES-EH.
➢ Mefuta eohle ea ES-EHs e tsamaellanang le maemo a fapaneng a karabelo e nepahetseng e lokela ho ithutoa ka bonngoe.
➢ High concentration Substrate kapa sehlahisoa se nang le sona se ka sitisa tšebetso ea ES-EH.Leha ho le joalo, inhibition e ka imoloha ka ho eketsoa ha sehlopha sa substrate.