β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) e nang le boleng bo phahameng.Re ka fana ka COA, phano ea lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Haeba u thahasella sehlahisoa sena, ka kopo romella lintlha tse qaqileng ho kenyelletsa nomoro ea CAS, lebitso la sehlahisoa, bongata ho rona.Ka kopo ikopanye le:lchen@syncozymes.com
| Lebitso la Lik'hemik'hale | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Litlhaloso tse tšoanang | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Nomoro ea CAS | 53-59-8 |
| Boima ba Molek'hule | 743.41 |
| Foromo ea limolek'hule | C21H28N7O17P3 |
| Nomoro ea EINECS | 200-178-1 |
| mocheso oa polokelo. | Boloka sebakeng se lefifi, se se nang moea, Boloka ka sehatsetsing, ka tlas'a -20°C |
| ho qhibiliha | H2O: 50 mg/mL, e hlakileng, e mosehla hanyenyane |
| pka | pKa1 3.9;pKa2 6.1(ho 25℃) |
| λmax | 260nm(lit.) |
| Merck | 14,6348 |
| EPA Substance Registry System | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester e nang le 3-(aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, letsoai le ka hare (53-59- 8) |
| Ntho ea Teko | Litlhaloso |
| Ponahalo | Phofo e tšoeu ho isa ho e mosehla |
| Solubility | 200mg / ml ka metsi |
| boleng ba pH (100mg/ml) | 5.0–7.0 |
| Tlhahlobo ea UV Spectral E le 260 nm le pH 7.5 | (18±1.0)×10³L/mol/cm |
| Litaba (ka tlhahlobo ea enzymatic le G6PDH ho pH 7.5, ho sebelisoa spectrophotometer, abs.340nm, ho latela anhydrous basis) | ≥90.0% |
| Bohloeki (ka HPLC,% sebaka) | ≥95.0% |
| Likahare tsa metsi (ka KF) | ≤5% |
Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka thata lefifing, ho boloka nako e telele ho 2 ~ 8 ℃.
NADP ke coenzyme, e leng ntho eo ho eona nicotinamide adenine dinucleotide le molek'hule ea phosphate li tlangoang ke bond ea ester, 'me li teng hohle.lefatsheng la baeloji.Lintho tsa eona tsa lik'hemik'hale, mahlaseli a ho monya, foromo ea redox, joalo-joalo li tšoana le NAD (Coenzyme I).NADP e ka sebelisoa haholo karabelonge hlahisoa ke li-dehydrogenase tsa joala tse fapaneng, ketoreductases le li-oxidoreductase tse ling.Joalo ka: e ka fokotsoa ho NADPH ke li-dehydrogenase tse ngata joaloe le 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Leha ho le joalo, ha se hakaalo hore e khona ho itšoara le ba bangatali-dehydrogenase tse sebelisang NAD, ebile e ke ke ea hlakoloa ka kotloloho ke ketane ea phefumoloho.Ho fapana le NAD, e fumaneha haholo maemong a fokotsehileng liseleng tsa lintho tse phelang hantle.
Ho latela ts'ebeliso ea sehlahisoa, e ka aroloa ka limaraka tse latelang: sehlopha sa biotransformation, sehlopha sa tlhahlobo ea reagent, sehlopha sa lijo tsa bophelo bo botle.
Biotransformation grade: E ka sebelisoa bakeng sa ho kopanya li-intermediate tsa meriana le li-API, haholo-holo ka li-enzyme tsa catalytic, tse kang ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), joalo-joalo Ema.
Sehlopha sa diagent tsa tlhahlobo: Ka mefuta e fapaneng ea li-enzyme tsa tlhahlobo, joalo ka lisebelisoa tse tala tsa lisebelisoa tsa tlhahlobo.
Boemo ba lijo tsa bophelo bo botle: Ts'ebeliso ea tlatsetso ea lijo ea NADP e haholo ts'ebetsong ea lipatlisiso le nts'etsopele.
