β-Nicotinamide Mononucleotide (NMN)
Haufinyane tjena, ho na le litaba tse monate tšimong ea NMN - ka mor'a tlhahlobo e tiileng ke komiti ea litsebi ea US Food and Drug Administration (FDA) e nang le matla a ho laela, thepa e tala ea NMN ea Shangke Biopharmaceutical (Shanghai) Co., Ltd. ho ea e le "Shangke Bio") e amohetsoe ke United States tumello ea FDA NDI e tiisa hore thepa ea eona e tala ea NMN e ka sebelisoa ka molao ho hlahisa, ho rekisa le ho khothaletsa lisebelisoa tsa lijo United States, 'me e ka fumanoa ho ofisiri ea FDA. Sebaka sa marang-rang e le sesebelisoa se secha sa tlatsetso ea lijo, nomoro ea 1247.
FDA NDI ke sistimi ea setifikeiti ea bohlokoa ka ho fetisisa 'marakeng oa US.Ho fumana setifikeiti sena ha ho bolele feela hore polokeho le boleng ba lihlahisoa tsa Shangke Bio lie ananelwa haholo, empa hape e thusa ntshetsopeleng e tsitsitseng e tsitsitseng ya indasteri ya NMN qetellong.
| Lebitso la Lik'hemik'hale | β-Nicotinamide Mononucleotide |
| Litlhaloso tse tšoanang | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Nomoro ea CAS | 1094-61-7 |
| Boima ba Molek'hule | 334.22 |
| Foromo ea limolek'hule | Setšoantšo sa C11H15N2O8P |
| EINECS: | 214-136-5 |
| Sebaka se qhibilihang | 166 °C(Dec.) |
| mocheso oa polokelo. | -20°C |
| ho qhibiliha | DMSO (Hanyenyane, E futhumetse), Methanol (Hanyenyane), Metsi (Hanyenyane) |
| sebopeho | Tiileng |
| mmala | Bosoeu ho isa Bosehla |
| Merck | 13,6697 |
| BRN | 3570187 |
| Botsitso: | Hygroscopic haholo |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Ntho ea Teko | Litlhaloso |
| Ponahalo | Phofo ea kristale e tšoeu ho isa bosoeu |
| Likahare tsa sodium | ≤1% |
| boleng ba pH (100mg/ml) | 2.0~4.0 |
| Bohloeki | ≥99.0% |
| Likahare tsa metsi | ≤1% |
| Litšepe tse boima | <10ppm |
| Arsenic | <0.5ppm |
| Ketapele | <0.5ppm |
| Mercury | <0.1ppm |
| Cadmium | <0.5ppm |
| Masala a qhibilihang | Ethanol≤1000ppm |
| Kakaretso ea Aerobic Microbial Count | <750cfu/g |
| Yeast & Mold | <25cfu/g |
| Kakaretso ea coliform | ≤0.92MPN/g |
| E. Coli | E mpe |
| Salmonella | E mpe |
| Staph.Aureus | E mpe |
| Assay (ka lebaka la anhydrous) | ≥99.0% |
| Sekhahla sa sieving | ≥95% |
| Boima ba bongata | Tlaleha bakeng sa tlhahisoleseding |
Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka har'a lijalo tse thata, tse sa boneng khanya, bakeng sa polokelo ea nako e telele, boloka mocheso oa 2 ~ 8°C kapa ka tlase.
Nicotinamide Mononucleotide (NMN) ke mofuta o mocha oa vithamine B3 eo e leng selelekela sa mohato o le mong ho NAD+ (Nicotinamide Adenine Dinucleotide).NMN ke motlatsi oa pele oa cellular oa NAD + ho netefatsoa hore o sebetsa ho khutlisetsa lisele ka har'a vivo.
Nicotinamide Adenine Dinucleotide (NAD) ke e 'ngoe ea limolek'hule tsa bohlokoa le tse khahlisang' meleng.E hlokahala bakeng sa karabelo ea enzymatic e fetang 500 mme e bapala karolo ea bohlokoa taolong ea hoo e batlang e le lits'ebetso tsohle tse kholo tsa tlhaho (Ansari le Raghava, 2010).Ka holim'a tsohle, e ka 'na ea re lumella ho phela bophelo bo botle le bo bolelele.
Nicotinamide Adenine Dinucleotide (NAD) e teng ka sebopeho sa eona se nang le oxidized (NAD+) kapa sebopeho se fokotsehileng (NADH), e leng li-cofactors tsa bohlokoa tsa mefuta e mengata ea oxireductase.
SyncoZyems e le ea pele ea ho fumana FDA NDI NMN e lumelletsoeng khoebo ea tlhahiso ea thepa e tala, e emela ofisiri ea FDA e amohela NMN joalo ka mofuta o mocha oa thepa o ka qalang ho amoheloa le ho amoheloa bakeng sa metsoako ea lijo United States.
