β-Nicotinamide Mononucleotide (NMN)
Haufinyane tjena, ho na le litaba tse monate lefapheng la NMN - kamora tlhahlobo e tiileng ke komiti ea litsebi ea mokhatlo o nang le matla oa Tsamaiso ea Lijo le Lithethefatsi oa US (FDA), lisebelisoa tse tala tsa NMN tsa Shangke Biopharmaceutical (Shanghai) Co., Ltd. (tseo ho thoeng ke "Shangke Bio") li amohetsoe ke tumello ea United States ea FDA NDI e tiisa hore lisebelisoa tsa eona tse tala tsa NMN li ka sebelisoa ka molao tlhahisong, thekisong le papatsong ea li-supplement tsa lijo United States, 'me li ka fumanoa webosaeteng ea semmuso ea FDA e le lisebelisoa tse ncha tsa tlatsetso ea lijo, nomoro ea 1247.
FDA NDI ke sistimi ea bohlokoa ka ho fetisisa ea setifikeiti 'marakeng oa Amerika. Ho fumana setifikeiti sena ha ho bolele feela hore polokeho le boleng ba lihlahisoa tsa Shangke Bio kee ananeloa haholo, empa hape e thusa ntshetsopele e tswelang pele ya indasteri ya NMN ha nako e ntse e ya.
| Lebitso la Khemik'hale | β-Nicotinamide Mononucleotide |
| Mantsoe a tšoanang | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Nomoro ea CAS | 1094-61-7 |
| Boima ba limolek'hule | 334.22 |
| Foromo ea limolek'hule | C11H15N2O8P |
| EINECS: | 214-136-5 |
| Sebaka sa ho qhibiliha | 166 °C (Tshitwe) |
| mocheso oa polokelo. | -20°C |
| ho qhibiliha ha metsi | DMSO (Hanyane, e futhumetse), Methanol (Hanyane), Metsi (Hanyane) |
| foromo | E tiileng |
| 'mala | Ho tloha ho Bosweu ho isa ho Bosehla |
| Merck | 13,6697 |
| BRN | 3570187 |
| Botsitso: | Hygroscopic haholo |
| InChIKey | DAYLJWODMOQEW-TURQNECASA-N |
| Ntho ea Teko | Litlhaloso |
| Ponahalo | Phofo e kristale e tšoeu ho isa ho e tšoeu |
| Sekhahla sa sodium | ≤1% |
| boleng ba pH (100mg/ml) | 2.0~4.0 |
| Bohloeki | ≥99.0% |
| Metsi a mangata | ≤1% |
| Litšepe tse boima | <10ppm |
| Arsenic | <0.5ppm |
| Moetapele | <0.5ppm |
| Mercury | <0.1ppm |
| Cadmium | <0.5ppm |
| Masalla a solvent | Ethanol≤1000ppm |
| Palo yohle ya dikokwana-hloko tsa Aerobic | <750cfu/g |
| Tomoso le Hlobo | <25cfu/g |
| Kakaretso ea coliform | ≤0.92MPN/g |
| E. Coli | Tse mpe |
| Salmonella | Tse mpe |
| Staph. Aureus | Tse mpe |
| Teko (ka motheo wa anhydrous) | ≥99.0% |
| Sekhahla sa ho thiba | ≥95% |
| Bongata ba bongata | Tlaleha bakeng sa tlhahisoleseling |
Sephutheloana:Botlolo, mokotlana oa foile ea aluminium, 25kg/Moqomo oa Khateboto, kapa ho latela tlhoko ea moreki.
Boemo ba Polokelo:Boloka ka har'a lijana tse tiileng, tse sa keneleng khanya, bakeng sa polokelo e telele, boloka mochesong oa 2 ~ 8°C kapa ka tlase.
Nicotinamide Mononucleotide (NMN) ke mofuta o mocha oa vithamine B3 e leng selelekela sa NAD+ (Nicotinamide Adenine Dinucleotide) mohato o le mong. NMN ke motsosolosi oa pele oa NAD+ oa sele o pakiloeng hore o sebetsa ho tsosolosa lisele ka har'a 'mele.
Nicotinamide Adenine Dinucleotide (NAD) ke e 'ngoe ea limolek'hule tsa bohlokoa ka ho fetisisa le tse khahlisang 'meleng. E hlokahala bakeng sa liketso tse fetang 500 tsa enzymatic 'me e bapala karolo ea bohlokoa taolong ea hoo e ka bang lits'ebetso tsohle tse kholo tsa baeloji (Ansari le Raghava, 2010). Ka holim'a tsohle, e ka re lumella ho phela bophelo bo botle le bo bolelele.
Nicotinamide Adenine Dinucleotide (NAD) e teng ka sebopeho sa yona se nang le oxidized (NAD+) kapa ka sebopeho se fokoditsweng (NADH), e leng di-cofactor tsa bohlokwa tsa di-oxireductase tse mmalwa.
SyncoZyems ke ea pele ho fumana k'hamphani ea tlhahiso ea lihlahisoa tse tala e amohetsoeng ke FDA NDI NMN, e emela semmuso sa FDA se amohelang NMN joalo ka mofuta o mocha oa thepa o ka qala ho amoheloa le ho amoheloa bakeng sa metsoako ea tlatsetso ea lijo United States.
