β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. ke moetsi le mofani ea ka sehloohong oa β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) ka boleng bo holimo. Re ka fana ka COA, thomello ea lefats'e ka bophara, bongata bo bonyenyane le bo bongata bo fumanehang. Haeba u na le thahasello sehlahisoa sena, ka kopo romela tlhahisoleseling e qaqileng e kenyeletsang nomoro ea CAS, lebitso la sehlahisoa, bongata ho rona. Ka kopo ikopanye le:lchen@syncozymes.com
| Lebitso la Khemik'hale | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Mantsoe a tšoanang | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Nomoro ea CAS | 53-59-8 |
| Boima ba limolek'hule | 743.41 |
| Foromo ea limolek'hule | C21H28N7O17P3 |
| Nomoro ea EINECS | 200-178-1 |
| mocheso oa polokelo. | Boloka sebakeng se lefifi, sepakapakeng se sa phutholohang, Boloka ka sehatsetsing, ka tlase ho -20°C |
| ho qhibiliha ha metsi | H2O: 50 mg/mL, e hlakile, e mosehla hanyane |
| pka | pKa1 3.9; pKa2 6.1 (ka 25℃) |
| λmax | 260nm (e bonesitsoeng) |
| Merck | 14,6348 |
| Sistimi ea Ngoliso ea Lithethefatsi ea EPA | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester e nang le 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, letsoai la ka hare (53-59-8) |
| Ntho ea Teko | Litlhaloso |
| Ponahalo | Phofo e tšoeu ho isa ho e mosehla |
| Ho qhibiliha ha metsi | 200mg/ml ka metsing |
| boleng ba pH (100mg/ml) | 5.0～7.0 |
| Tlhahlobo ea Li-spectral tsa UV ho 260 nm le pH 7.5 | (18±1.0)×10³L/mol/cm |
| Dikahare (ka tlhahlobo ya enzymatic ka G6PDH ho pH 7.5, ho sebediswa spectrophotometer, abs.340nm, motheong wa anhydrous) | ≥90.0% |
| Bohloeki (ka HPLC, %sebaka) | ≥95.0% |
| Bongata ba metsi (ka KF) | ≤5% |
Sephutheloana:Botlolo, mokotlana oa foile ea aluminium, 25kg/Moqomo oa Khateboto, kapa ho latela tlhoko ea moreki.
Boemo ba Polokelo:Boloka e koetsoe ka thata lefifing, bakeng sa polokelo e telele e boloke ho 2 ~ 8℃.
NADP ke coenzyme, e leng ntho eo nicotinamide adenine dinucleotide le molek'hule ea phosphate li tlamiloeng ka tlamo ea ester, 'me li teng haholo.lefatšeng la baeloji. Thepa ea eona ea lik'hemik'hale, sekala sa ho monya, sebopeho sa redox, jj. li tšoana le NAD (Coenzyme I). NADP e ka sebelisoa haholo liketsonge susumetsoang ke di-dehydrogenase tse fapaneng tsa jwala, di-ketoreductase le di-oxidoreductase tse ding. Jwalo ka: e ka fokotswa ho ba NADPH ke di-dehydrogenase tse ngata jwalo kae le 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44). Leha ho le jwalo, ha se hakaalo hore e kgona ho arabela le tse ngatadi-dehydrogenase tse sebedisang NAD, leha e le hore di ka oxidation ka ho toba ke ketane ya ho hema. Ho fapana le NAD, e teng haholo-holo ka boemo bo fokotsehileng diseleng tsa diphedi tse phelang ka aerobic.
Ho ea ka tšebeliso ea sehlahisoa, se ka aroloa ka lihlopha tse latelang: sehlopha sa biotransformation, sehlopha sa diagnostic reagent, sehlopha sa lijo tse phetseng hantle.
Kereiti ea phetoho ea bio: E ka sebelisoa bakeng sa ho kopanya metsoako ea meriana le li-API, haholo-holo ka li-enzyme tsa catalytic, tse kang ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), jj. Ema.
Sehlopha sa reagent ea tlhahlobo: Ka mefuta e fapaneng ea li-enzyme tsa tlhahlobo, e le thepa e tala ea lisebelisoa tsa tlhahlobo.
Sehlopha sa lijo tse phetseng hantle: Tšebeliso ea tlatsetso ea lijo ea NADP e etsoa haholo-holo ts'ebetsong ea lipatlisiso le nts'etsopele.
