Ketoreductase (KRED)

Tlhaloso e Khutšoanyane:

Mabapi le Ketoreductase

Li-Enzyme: Ke li-macromolecular biological catalysts, li-enzyme tse ngata ke liprotheine.

Ketoreductase: E boetse e bitsoa "Carbonyl reductase", ke li-enzyme tse susumetsang karabelo e ka fetohang ea redox lipakeng tsa aldehydes / ketone le joala, 'me li hloka li-coenzymes joalo ka H transmitter joalo ka NADH kapa NADPH.Ho na le lihlopha tse tharo tse kholo tsa KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), le Aldo-KetoReductases (AKRs).Mesebetsi ea matla ea boraro e tšoana, empa sebopeho le thepa li fapane haholo.

Mobile/Wechat/WhatsApp: +86-13681683526

E-mail:lchen@syncozymes.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Mabapi le Ketoreductase:

KRED ho tsoa ho SyncoZymes: Ho na le mefuta e 191 ea lihlahisoa tsa enzyme ea KRED (Palo e le ES-KRED-101~ES-KRED-291) e ntlafalitsoeng ke SyncoZymes.SZ-KRED e ka sebelisoa haholo ho fokotsa regio le stereoelective ea aldehydes, beta-ketone esters, α-ketone esters le ketone.

Mofuta oa karabelo ea Catalytic:

Lintlha tsa Sehlahisoa:

Li-enzyme	Khoutu ea Sehlahisoa	Tlhaloso
Phofo ea enzyme	Phofo ea enzyme	sehlopha sa 187 Ketoreductases, 50 mg ka 'ngoe 187 lintho * 50mg / ntho, kapa bongata bo bong
Skrine Kit (SynKit)	ES-KRED-18100	sehlopha sa 181 Ketoreductases, 1 mg ka 'ngoe lintho tse 181 * 1mg / ntho

Melemo:

★ Boemo bo phahameng ba substrate.
★ Khetho e matla ea chiral.
★ Ho sebetsa ka mokhoa o phahameng oa phetoho.
★ Lihlahisoa tse fokolang.
★ Maemo a bonolo a karabelo.
★ Ho baballa tikoloho.

Litaelo tsa tšebeliso:

➢ Tlhahlobo ea li-enzyme e lokela ho etsoa bakeng sa li-substrate tse khethehileng ka lebaka la sebopeho sa substrate, 'me u fumane enzyme e susumetsang karoloana e lebisitsoeng e nang le phello e ntle ka ho fetisisa.
➢ Le ka mohla u se ke ua kopana le maemo a feteletseng joalo ka: mocheso o phahameng, pH e phahameng/tlase le sehlapolli sa tlhaho se nang le mahloriso a holimo.
➢ Ka tloaelo, sistimi ea karabelo e tlameha ho kenyelletsa substrate, tharollo ea buffer, coenzymes(NAD(H) kapa NADP(H)), sistimi ea coenzyme regeneration(mohlala, glucose le glucose dehydrogenase).
➢ KRED e lokela ho eketsoa ho qetela tsamaisong ea karabelo, kamora hore pH le mocheso li lokisoe ho latela boemo ba karabelo.
➢ Mefuta eohle ea KRED e na le maemo a fapaneng a karabelo, ka hona e 'ngoe le e 'ngoe ea tsona e lokela ho ithutoa ka bonngoe.