SyncoZymes

lihlahisoa

Transaldolase (TAL)

Tlhaloso e Khutšoanyane:

Mabapi le Transaldolase

ES-TAL (Transaldolase): haholo-holo e bua ka threonine transaldolases, e ka susumetsang karabelo ea ho kopanya lihlahisoa tsa β-hydroxyphenylalanine ka threonine le benzaldehyde derivatives.TAL ke enzyme e itšetlehileng ka PLP.Ho na le mofuta o le mong feela oa sehlahisoa sa enzyme ea TAL (Palo e le ES-TAL101) e entsoeng ke SyncoZymes, e ka sebelisoang ho kopanya β-hydroxyphenylalanine le lihlahisoa tsa eona.

Mofuta oa karabelo ea Catalytic:

Transaldolase TAL

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E-mail:lchen@syncozymes.com


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Melemo:

★ Boemo bo phahameng ba substrate.
★ Khetho e matla ea chiral.
★ Phetoho e phahameng.
★ Lihlahisoa tse fokolang.
★ Maemo a bonolo a karabelo.
★ Ho baballa tikoloho.

Litaelo tsa tšebeliso:

➢ Ka tloaelo, sistimi ea karabelo e tlameha ho kenyelletsa substrate, tharollo ea buffer, enzyme, PLP, Mg2+.
➢ TAL e lokela ho ekeletsoa ho qetela tsamaisong ea karabelo, ka mor'a hore pH le mocheso li lokisoe ho latela boemo ba karabelo.

Mehlala ea Tšebeliso:

Mohlala 1(Synthesis of (2S, 3R)-p-methylsulfonyl phenylserine from p-methylsulfonyl benzaldehyde and threonine)(1):

Transaldolase TAL2

Polokelo:

Boloka lilemo tse 2 ka tlase ho -20 ℃.

Tlhokomeliso:

Le ka mohla u se ke ua kopana le maemo a feteletseng a kang: mocheso o phahameng, pH e phahameng / tlase le solvent e phahameng ea organic.

Litšupiso:

1. CN109836362B


  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona