-
Oxynitrilases (HNL)
Mabapi le li-oxynitrilases
ES-HNLs: Enzyme ea sehlopha e etsang hore enantioselectively e tlatse ho eketsoa ha HCN ho aldehydes (ketones) ho fumana R kapa S mofuta oa cyanide alcohols, e ka fetoloang habonolo mefuteng e mengata ea lithethefatsi kapa li-intermediate tsa lithethefatsi ka mokhoa oa lik'hemik'hale.
Ho na le mefuta e 29 ea lihlahisoa tsa oxynitrilase (Palo e le ES-HNL-101～ES-HNL-129) e ntlafalitsoeng ke SyncoZymes.SZ-HNL ke sesebelisoa se molemo ho regio- le stereo- selective synthesis ea (R) -cyanohydrins kapa (S) -cyanohydrins ho tsoa mefuteng e fapaneng ea monko o monate, aliphatic le heterocyclic aldehydes kapa esita le ketone.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Nitro reductase (NTR)
Mabapi le nitro reductase
ES-NTRs: Ke li-flavoenzymes tse susumetsang phokotso e itšetlehileng ka NAD(P)H ea lihlopha tsa nitro ka metsoako ea nitroaromatic le nitroheterocyclic ho hydroxylamino le/kapa li-amino derivatives.Li sebelisoa haholo ho organic synthesis ea monko o monate oa hydroxylamine le amine e nkhang hamonate, kalafo ea hlahala, tlhahlobo ea baeloji le ho senyeha ha lintho tse silafatsang tikoloho.Ho na le mefuta e 12 ea lihlahisoa tsa Nitro reductase (NTR) (Palo e le ES-NTR-101~ES-NTR-112) e entsoeng ke SyncoZymes.
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Aldolase (DERA)
ES-DERAs: E ka thusa ka katleho tlatsetso ea stereoselective ea li-ketone tsa bafani ho li-aldehyde tsa receptor.Ho feta moo, karabelo e ka etsoa ka tharollo ea metsi ea pH e sa nke lehlakore ntle le mehato e khethehileng ea tšireletso.Ke ba sehlopha sa I aldolase, se etsang Shiff base ts'ebetsong ea ts'ebetso.Substrate e kopantsoe ka mokhoa o kopanetsoeng le sehlopha sa amino sa sebaka se sebetsang ho qala ho senya le ho thehoa ha tlamo.Phapang lipakeng tsa li-DERA le li-aldolase tse ling ke hore li-substrates tseo li li hlahisang ke aldehydes 'me li ka ba le condensation e tsoelang pele ea aldehydes.
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Cytochrome P450 monooxygenase (CYP)
Mabapi le CYP
ES-CYPs: Sehlopha sa li-enzyme tsa redox tse nang le mercaptan-heme e le setsi se sebetsang sa ho susumetsa phetisetso ea oksijene.Ke li-oksijene tsa ho qetela 'me li hloka heme ho kenya oksijene tšebetsong.
Cytochrome P450 monooxygenase e etsa hore oxidation, epoxidation le hydroxylation ea alkyl, hydroxylation le oxidation ea ammonia, oxidation ea sebabole, dealkylation (oksijene, sebabole, ammonia), oxidative dehydrogenation, deamination le dehalogenation.
Ho na le mefuta e 8 ea lihlahisoa tsa cytochrome P450 monooxygenase (Palo e le ES-CYP-101～ES-CYP-108) e ntlafalitsoeng ke SyncoZymes.Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Alcohol oxidase (AOX)
Mabapi le oxidase ea joala
ES-AOXs: Li-enzyme tsena li khona ho etsa hore oxidation ea lino tse mafura kapa aryl-alcohols li etse aldehydes.Ba sebelisa oksijene ea molek'hule empa ha e hloke cofactor e kentsoeng ka ntle, le hydrogen peroxide e hlahisoa.
Ho na le mefuta e 6 ea lihlahisoa tsa alcohol oxidase (Palo e le ES-AOX-101~ES-AOX-106) e ntlafalitsoeng ke SyncoZymes.ES-AOX101 le ES-AOX102 li khetha li-aliphatic alcohol substrates, ES-AOX103~ ES-AOX105 li khetha li-aromatic alcohol substrates, 'me ES-AOX106 ke cholesterol oxidase.SZ-AOX ke sesebelisoa se sebetsang sa ho etsa hore oxidation ea lino tse mafura kapa aryl-alcohols li hlahise aldehydes.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
D-Amino acid dehydrogenase (D-AADH)
Mabapi le D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): enzyme e ka fokotsang 2-keto acid hore e be D-amino acid e lumellanang.Karabelo e hloka NADP(H) le mofani oa ammonia oa inorganic (joalo ka ammonia kapa ammonium ion).Ho na le mefuta e 17 ea D-amino acid dehydrogenases (Palo e le ES-DAADH-101~ ES-DAADH-117) e ntlafalitsoeng ke SyncoZymes.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Esterase&Lipase (PLE&CALB)
Mabapi le Esterase&Lipase
ES-PLEs: Sehlopha sa li-hydrolases tse susumetsang ho thehoa le ho senyeha ha li-ester bond.Ba ka nka karolo mefuteng e mengata ea karabelo ea biochemical, joalo ka esterification, transesterification le hydrolysis.Li sebelisoa haholo likarolong tse ngata tse kang ho lokisa lijo, indasteri ea lik'hemik'hale, biomedicine, meriana ea chiral le phekolo ea tikoloho.
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Epoxide hydrolase (EH)
Mabapi le epoxide hydrolase
EH ke ether hydrolase e susumetsang stereoelective hydrolysis ea racemic epoxides ho hlahisa 1, 2-diol le epoxides optically active, e ka sebelisetsoang qeto ea chiral ea epoxides kapa ho lokisetsa li-chiral diols.Li sebelisoa haholo meriana le mafapheng a mang.Ho na le mefuta e 3 ea lihlahisoa tsa epoxide hydrolases (Palo e le ES-EH-101～ES-EH-103) e ntlafalitsoeng ke SyncoZymes.ES-EH ke sesebelisoa se sebetsang sa ho etsa tlhahiso ea li-alcohols tsa chiral ka stereoelective hydrolysis ea aliphatic le aromatics epoxides.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Formate dehydrogenase (FDH)
Mabapi le Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH e susumetsa dehydrogenation ea ammonium formate ho hlahisa carbon dioxide le ammonia, le ho fokotsa NAD ho NADH ka NAD e le electron receptor.FDH hangata e sebelisetsoa ho nchafatsa coenzyme NADH.Ho na le mefuta e 4 ea lihlahisoa tsa enzyme tsa FDH (ES-FDH-101~ES-FDH-104) tse entsoeng ke SyncoZymes, tseo har'a tsona ES-FDH102 e nang le ts'ebetso e phahameng ka ho fetisisa 'me ke FDH e khothalletsoang haholo.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Glucose dehydrogenase (GDH)
Mabapi le Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH e susumetsa dehydrogenation ea tsoekere ho hlahisa gluconic acid (lactone), le ho fokotsa NAD (P) + ho NAD (P) H, le NAD (P) + e le electron receptor.GDH e atisa ho sebelisoa bakeng sa tsosoloso ea coenzyme NAD(P)H masimong a biocatalysis ka enzyme e meng e ka sehloohong.Ho na le mefuta ea 10 ea lihlahisoa tsa enzyme ea GDH (ES-GDH-101~ES-GDH-110) e entsoeng ke SyncoZymes, eo har'a eona ES-GDH110 e nang le ts'ebetso e phahameng ka ho fetisisa 'me ke eona e khothalletsoang haholo-holo GDH.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Monoamine oxidase (MAO)
Mabapi le Monoamine oxidase
ES-MAO(Monoamine oxidase): MAO e etsa hore ho be le oxidative deamination ea monoamine ho hlahisa hydrogen peroxide, ammonia le aldehyde e tsamaisanang.Ts'ebetsong ea ts'ebetso, oksijene ea hlokahala joalo ka oxidant.Ho na le mefuta e 6 ea lihlahisoa tsa enzyme tsa MAO (Palo e le ES-MAO-101～ES-MAO-106) e ntlafalitsoeng ke SyncoZymes, e ka sebelisoang ho oxidative deamination ea metsoako ea monoamine.
Mofuta oa karabelo ea Catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
-
Lactate Dehydrogenase (LDH)
Mabapi le Lactate dehydrogenase
Ho na le mofuta o le mong oa sehlahisoa sa enzyme ea LDH (Palo e le ES-LDH) e ntlafalitsoeng ke SyncoZymes.LDH e ka baka phokotso ea pyruvate ho L-lactic acid, kapa phokotso ea li-α-keto acid tse ling tse tšoanang.Ts'ebetsong ea catalysis, NADH ea hlokahala joalo ka sepalangoang sa hydrogen.
Mofuta oa karabelo ea lactate dehydrogenasecatalytic
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
