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Li-Oxynitrilase (HNL)
Mabapi le li-oxynitrilase
ES-HNLs: Enzyme ea sehlopha e susumetsang ka mokhoa o khethollang ho eketsoa ha HCN ho aldehydes (ketones) ho fumana alcohols ea cyanide ea mofuta oa R kapa S, e ka fetoloang habonolo hore e be mefuta e mengata ea lithethefatsi kapa li-intermediate tsa lithethefatsi ka mokhoa oa lik'hemik'hale.
Ho na le mefuta e 29 ea lihlahisoa tsa oxynitrilase (Nomoro e le ES-HNL-101～ES-HNL-129) e ntlafalitsoeng ke SyncoZymes. SZ-HNL ke sesebelisoa se thusang ho kopanya libaka le libaka tsa (R)-cyanohydrins kapa (S)-cyanohydrins ho tsoa mefuta e fapaneng ea aldehydes kapa esita le li-ketone tse nkhang hamonate, tse nang le monko o monate le tse sa fetoheng.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Nitro reductase (NTR)
Mabapi le nitro reductase
ES-NTRs: Ke li-flavoenzymes tse susumetsang phokotso e itšetlehileng ka NAD(P)H ea lihlopha tsa nitro tse itšetlehileng ka metsoako ea nitroaromatic le nitroheterocyclic ho ea ho hydroxylamino le/kapa li-amino derivatives. Li sebelisoa haholo ho etseng organic ea aromatic hydroxylamine le aromatic amine, kalafo ea hlahala, ho lemoha baeloji le ho senyeha ha litšila tsa tikoloho. Ho na le mefuta e 12 ea lihlahisoa tsa Nitro reductase (NTR) (Nomoro e le ES-NTR-101~ES-NTR-112) e ntlafalitsoeng ke SyncoZymes.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERA: E ka susumetsa ka katleho ho eketsoa ha di-ketone tsa bafani ho di-receptor aldehydes ka stereoselective. Ho feta moo, karabelo e ka etswa ka tharollo ya metsi ya pH e sa nke lehlakore ntle le mehato e ikgethang ya tshireletso. Ke ya sehlopha sa I aldolase, e bopang motheo wa Shiff tshebetsong ya catalytic. Substrate e hokahantswe ka kopanelo le sehlopha sa amino sa sebaka se sebetsang ho qala ho robeha le ho thehwa ha tlamo. Phapang pakeng tsa DERA le di-aldolase tse ding ke hore di-substrate tseo di di susumetsang ke di-aldehydes mme di ka feta ho kolobisong ho sa feleng ha di-aldehydes.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Mabapi le CYP
ES-CYPs: Sehlopha sa li-enzyme tsa redox tse nang le mercaptan-heme e le setsi se sebetsang sa ho susumetsa phetiso ea oksijene. Ke li-oxygenase tsa ho qetela 'me li hloka heme ho kenya tšebetsong oksijene.
Cytochrome P450 monooxygenase e susumetsa ho kenngwa ha oksijene, ho kenngwa ha oksijene le ho kenngwa ha hydroxylation ya alkyl, ho kenngwa ha hydroxylation le ho kenngwa ha ammonia, ho kenngwa ha sebabole, dealkylation (oksijene, sebabole, ammonia), ho kenngwa ha oksijene ka oxidative, ho ntshwa ha oksijene le ho ntshwa ha halogenation.
Ho na le mefuta e 8 ea lihlahisoa tsa cytochrome P450 monooxygenase (Nomoro e le ES-CYP-101～ES-CYP-108) e ntlafalitsoeng ke SyncoZymes.Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Oxidase ea joala (AOX)
Mabapi le oxidase ea joala
ES-AOXs: Li-enzyme tsena li khona ho susumetsa oxidation ea mafura a alcohols kapa aryl-alcohols ho etsa aldehydes. Li sebelisa oksijene ea limolek'hule empa ha li hloke cofactor e ekelitsoeng ka ntle, le hydrogen peroxide e hlahisoang.
Ho na le mefuta e 6 ea lihlahisoa tsa oxidase ea joala (Nomoro e le ES-AOX-101~ES-AOX-106) e ntlafalitsoeng ke SyncoZymes. ES-AOX101 le ES-AOX102 li khetha li-substrate tsa alcohol tsa aliphatic, ES-AOX103~ ES-AOX105 li khetha li-substrate tsa alcohol tse nkhang hamonate, 'me ES-AOX106 ke cholesterol oxidase. SZ-AOX ke sesebelisoa se thusang ho potlakisa oxidation ea alcohols tse mafura kapa aryl-alcohols ho hlahisa aldehydes.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Mabapi le D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): enzyme e ka fokotsang 2-keto acid ho ba D-amino acid e tsamaellanang. Karabelo e hloka NADP(H) le inorganic ammonia donor (jwalo ka ammonia kapa ammonium ion). Ho na le mefuta e 17 ya D-amino acid dehydrogenases (Palo e le ES-DAADH-101~ ES-DAADH-117) e ntshetswang pele ke SyncoZymes.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Esterase le Lipase (PLE le CALB)
Mabapi le Esterase le Lipase
ES-PLE: Sehlopha sa li-hydrolase tse susumetsang ho thehoa le ho robeha ha li-ester bond. Li ka nka karolo mefuteng e mengata ea lik'hemik'hale, joalo ka esterification, transesterification le hydrolysis. Li sebelisoa haholo masimong a mangata a kang ts'ebetso ea lijo, indasteri ea lik'hemik'hale, biomedicine, meriana ea chiral le kalafo ea tikoloho.
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Mabapi le epoxide hydrolase
EH ke ether hydrolase e susumetsang hydrolysis ea stereoselective ea li-epoxide tsa racemic ho hlahisa li-epoxide tse 1, 2-diol le tse sebetsang ka optically, tse ka sebelisoang bakeng sa qeto ea chiral ea li-epoxide kapa ho lokisoa ha li-diols tsa chiral. Li sebelisoa haholo merianeng le mafapheng a mang. Ho na le mefuta e 3 ea lihlahisoa tsa epoxide hydrolases (Nomoro e le ES-EH-101～ES-EH-103) e ntlafalitsoeng ke SyncoZymes. ES-EH ke sesebelisoa se thusang ho susumetsa tlhahiso ea li-alcohol tsa chiral ka hydrolysis ea stereoselective ea li-epoxide tsa aliphatic le aromatic.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Mabapi le Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH e susumetsa ho ntšoa ha ammonium formate ho hlahisa carbon dioxide le ammonia, le ho fokotsa NAD ho NADH ka NAD e le electron receptor. FDH e atisa ho sebelisoa bakeng sa ho nchafatsa coenzyme NADH. Ho na le mefuta e 4 ea lihlahisoa tsa enzyme ea FDH (ES-FDH-101~ES-FDH-104) tse ntlafalitsoeng ke SyncoZymes, tseo har'a tsona ES-FDH102 e nang le ts'ebetso e phahameng ka ho fetisisa 'me ke FDH e khothaletsoang haholo.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Mabapi le Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH e susumetsa ho ntšoa ha glucose ho hlahisa gluconic acid (lactone), le ho fokotsa NAD(P)+ ho NAD(P)H, ka NAD(P)+ e le receptor ea lielektrone. GDH e atisa ho sebelisoa bakeng sa ho nchafatsa coenzyme NAD(P)H masimong a biocatalysis ka enzyme e 'ngoe e kholo. Ho na le mefuta e 10 ea lihlahisoa tsa enzyme ea GDH (ES-GDH-101~ES-GDH-110) tse ntlafalitsoeng ke SyncoZymes, eo har'a eona ES-GDH110 e nang le ts'ebetso e phahameng ka ho fetisisa 'me ke GDH e khothaletsoang haholo.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Mabapi le Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO e susumetsa ho tlosoa ha oxidative ha monoamines ho hlahisa hydrogen peroxide, ammonia le aldehydes tse tsamaellanang. Ts'ebetsong ea catalytic, oksijene ea hlokahala e le oxidant. Ho na le mefuta e 6 ea lihlahisoa tsa enzyme ea MAO (Nomoro e le ES-MAO-101 ~ ES-MAO-106) e ntlafalitsoeng ke SyncoZymes, e ka sebelisoang ho tlosoa ha oxidative ha metsoako ea monoamine.
Mofuta oa karabelo ea catalytic:
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Mabapi le Lactate dehydrogenase
Ho na le mofuta o le mong oa sehlahisoa sa enzyme ea LDH (Nomoro e le ES-LDH) e ntlafalitsoeng ke SyncoZymes. LDH e ka susumetsa phokotso ea pyruvate ho L-lactic acid, kapa phokotso ea li-α-keto acid tse ling tse tšoanang. Ts'ebetsong ea catalysis, NADH ea hlokahala e le transporter ea haeterojene.
Lactate dehydrogenase mofuta oa karabelo ea catalytic
Selefouno/Wechat/WhatsApp: +86-13681683526
Imeile:lchen@syncozymes.com
