Aldolase (DERA)

Tlhaloso e Khutšoanyane:

ES-DERAs: E ka thusa ka katleho tlatsetso ea stereoselective ea li-ketone tsa bafani ho li-aldehyde tsa receptor.Ho feta moo, karabelo e ka etsoa ka tharollo ea metsi ea pH e sa nke lehlakore ntle le mehato e khethehileng ea tšireletso.Ke ba sehlopha sa I aldolase, se etsang Shiff base ts'ebetsong ea ts'ebetso.Substrate e kopantsoe ka mokhoa o kopanetsoeng le sehlopha sa amino sa sebaka se sebetsang ho qala ho senya le ho thehoa ha tlamo.Phapang lipakeng tsa li-DERA le li-aldolase tse ling ke hore li-substrates tseo li li hlahisang ke aldehydes 'me li ka ba le condensation e tsoelang pele ea aldehydes.

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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Mabapi le Aldolase:

Ho na le mefuta e 8 ea lihlahisoa tsa aldolase (Nomoro e le ES-DERA-101～ES-DERA-108) e ntlafalitsoeng ke SyncoZymes.SZ-DERA ke sesebelisoa se sebetsang ho thusa ho theha bond ea carbon-carbon bond ea enantioselective, e hlahisang litsi tse peli tsa chiral tlas'a maemo a bonolo a karabelo.

Mofuta oa karabelo ea Catalytic:

Mochine oa Catalytic:

Lintlha tsa Sehlahisoa:

Li-enzyme	Khoutu ea Sehlahisoa	Tlhaloso
Phofo ea enzyme	ES-DERA-101~ ES-DERA-108	sete ea 8 Aldolase, 50 mg ka 'ngoe lintho tse 8 * 50mg / ntho, kapa bongata bo bong
Skrine Kit (SynKit)	ES-DERA-800	sete ea 8 Aldolase, 1 mg ka 'ngoe lintho tse 8 * 1mg / ntho

Melemo:

★ Maqhubu a pharalletseng a substrate.
★ Phetoho e phahameng.
★ Lihlahisoa tse fokolang.
★ Maemo a bonolo a karabelo.
★ Ho baballa tikoloho.

Litaelo tsa tšebeliso:

➢ Ka tloaelo, sistimi ea karabelo e tlameha ho kenyelletsa substrate, buffer solution (optimum reaction pH) le ES-DERA.
➢ Mefuta eohle ea ES-DERA e tsamaellanang le maemo a fapaneng a karabelo e nepahetseng e lokela ho ithutoa ka bonngoe.
➢ ES-DERA e tlameha ho kenyelletsoa ho qetela tsamaisong ea karabelo ho boloka ts'ebetso.
➢ High concentration Substrate kapa sehlahisoa se nang le tsona se ka sitisa tšebetso ea ES-DERA.Leha ho le joalo, inhibition e ka imoloha ka ho eketsoa ha sehlopha sa substrate.