SyncoZymes

lihlahisoa

Cyclooxygenase (COX)

Tlhaloso e Khutšoanyane:

Mabapi le Cyclooxygenase

ES-COX (Cyclooxygenase): e susumetsa phetoho ea li-bond tsa C = C ho epoxide.Ho na le mefuta e 11 ea lihlahisoa tsa enzyme ea COX (Palo e le ES-COX101~ ES-COX-111) e ntlafalitsoeng ke SyncoZymes.Ho latela mekhoa e fapaneng ea catalytic, COX ea SyncoZymes e arotsoe ka haloperoxidase le styrene monooxygenase.ES-COX101, 102, 107-111 ke ea haloperoxidase, ha ES-COX103-106 e le ea styrene monooxygenase.

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E-mail:lchen@syncozymes.com


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Mabapi le Cyclooxygenase:

Mofuta oa karabelo ea Catalytic:

Haloperoxidase:

Cyclooxygenase COX2

Styrene monooxygenase:

Cyclooxygenase COX3

Lintlha tsa Sehlahisoa:

Cyclooxygenase COX
Li-enzyme Khoutu ea Sehlahisoa Tlhaloso
Phofo ea enzyme ES-COX-101~ ES-COX-110 sehlopha sa 10 NADH Cyclooxygenase, 50 mg e 'ngoe le e 'ngoe lintho tse 10 * 50mg / ntho, kapa bongata bo bong

Melemo:

★ Boemo bo phahameng ba substrate.
★ Khetho e matla ea chiral.
★ Phetoho e phahameng.
★ Lihlahisoa tse fokolang.
★ Maemo a bonolo a karabelo.
★ Ho baballa tikoloho.

Litaelo tsa tšebeliso:

➢ Ka tloaelo, haloperoxidase reaction system e kenyelletsa: substrate, buffer, enzyme, H2O2 le halogen ion.Sistimi ea karabelo ea styrene monooxygenase e kenyelletsa substrate, buffer, enzyme, coenzyme le coenzyme regeneration system.
➢ COX e lokela ho ekeletsoa ho qetela tsamaisong ea karabelo, ka mor'a hore pH le mocheso li lokisoe ho latela boemo ba karabelo.

Mehlala ea Tšebeliso:

Mohlala 1(Kakaretso ea li-derivatives tsa epoxy styrene ho tsoa ho li-styrene derivatives)(1):

Cyclooxygenase COX4

Tlhokomeliso: mehlala ea ts'ebeliso le litšupiso li reretsoe ho bonts'a boholo ba ts'ebeliso ea COX bakeng sa kutloisiso e bonolo, 'me ha e tsamaellane le enzyme e khethehileng ea SyncoZymes.

Polokelo:

Boloka lilemo tse 2 ka tlase ho -20 ℃.

Tlhokomeliso:

Le ka mohla u se ke ua kopana le maemo a feteletseng a kang: mocheso o phahameng, pH e phahameng / tlase le solvent e phahameng ea organic.

Litšupiso:

1. Lin, Hui, Yan Liu, le Zhong-Liu Wu.Tetrahedron: Asymmetry 22.2 (2011): 134-137.


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  • E 'ngoe:

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